Isaac L. Anderson (1780–1857) was a Presbyterian minister and the founder in 1819 of Southern and Western Theological Seminary in Maryville, Tennessee. In 1842 the seminary was renamed as Maryville College. A native of Rockbridge County, Virginia, Dr. Anderson was educated in a traditional log school house after he was taught to read and spell by his grandmother. Later he attended Liberty Hall Academy, present-day Washington and Lee University, in Lexington, Virginia.