Isaac Matongo (12 March 1947 – 2 May 2007) was a Zimbabwean politician and labor activist, born in Fort Victoria, Southern Rhodesia. Matongo was elected vice-president of the National Engineering Workers' Union in 1988, eventually serving in the same position with the Zimbabwe Congress of Trade Unions. He was the founding chairman of the Movement for Democratic Change (MDC), which is now the main opposition to the ZANU-PF party led by Robert Mugabe.