Isaac Isanga Musumba is a Ugandan lawyer and politician. He served as the State Minister for Regional Foreign Affairs, from June 2006 until May 2011. In the cabinet reshuffle on 27 May 2011, he was dropped from the cabinet and was replaced by Asuman Kiyingi. He also served as the elected Member of Parliament (MP), representing "Buzaaya County", Kamuli District, from 1996 until 2011.