Isabela State University - Ilagan City Campus was one of the three original campuses merged to become the first state university in Cagayan Valley Region, the others were Cabagan Campus and Echague Campus. Through the Presidential Decree 1434 signed by former President Ferdinand Marcos on June 10,1978, the Isabela State University was created. The Isabela College of Agriculture in Echague and the Cagayan Valley Institute of Technology in Cabagan were merged to form the state university.