Isadore Manuel Singer (born May 3, 1924) is an Institute Professor in the Department of Mathematics at the Massachusetts Institute of Technology. He is noted for his work with Michael Atiyah proving the Atiyah–Singer index theorem in 1962, which paved the way for new interactions between pure mathematics and theoretical physics.He was born in Detroit, Michigan, and received his undergraduate degree from the University of Michigan in 1944. After obtaining his M.S. and Ph.D.