Isanti County (/aɪˈsæntiː/ eye-SAN-tee) is a county located in the U.S. state of Minnesota. As of the 2010 census, the population was 37,816. Its county seat is Cambridge. Isanti is derived from a Sioux name meaning "knife".Isanti County is included in the Minneapolis-St. Paul-Bloomington, MN Metropolitan Statistical Area.