Ismihan Sultan (c. 1544 – 7 August 1585) was an Ottoman princess, the daughter of Selim II (reign 1566-74) and Nurbanu Sultan. She was the granddaughter of Suleiman the Magnificent (reign 1520-66) and his favourite consort and legal wife Hürrem Sultan, sister of Sultan Murad III (reign 1574-95) and aunt of Sultan Mehmed III (reign 1596-1603).