Jan Franco (active 1586–1615) was a physician, mathematician and astronomer who compiled almanacs. He was born in the village of Eersel in the Duchy of Brabant and studied medicine at the University of Leuven. He settled in Brussels to practice medicine and was given the freedom of the city. He was a practicing physician at least until 1594. As he had studied both medicine and mathematics, he was asked to calculate the ephemerides, for purposes of medical astrology.