Jimmy Lee Smithson, known as Jim L. Smithson (born September 15, 1943), is a conservative Republican former member of the Arkansas House of Representatives who is remembered for cosponsoring legislation in his state to allow generic substitution of prescription medications. A registered pharmacist from Marshall, the seat of Searcy County in northwestern Arkansas, Smithson served in the House from January 1, 1975, to December 31, 1984.