James M. Pyne (born November 23, 1971) is a former American college and professional football player who was an offensive lineman in the National Football League (NFL) for nine seasons. He played college football for Virginia Tech, and earned All-American honors. Drafted late in the seventh round of the 1994 NFL Draft, Pyne became a reliable starter for the Tampa Bay Buccaneers, Detroit Lions, Cleveland Browns and Philadelphia Eagles of the NFL.