Sir John Warcup "Kappa" Cornforth, Jr., AC, CBE, FRS, FAA (7 September 1917 – 8 December 2013), was an Australian–British chemist who won the Nobel Prize in Chemistry in 1975 for his work on the stereochemistry of enzyme-catalysed reactions, becoming the only Nobel laureate born in New South Wales.Cornforth investigated enzymes that catalyse changes in organic compounds, the substrates, by taking the place of hydrogen atoms in a substrate's chains and rings.