John Wayles (January 31, 1715 – May 28, 1773) was a planter, slave trader and lawyer in the Virginia Colony. He is historically best known as the father-in-law of Thomas Jefferson, third President of the United States.Wayles is widely believed to have taken his mixed-race slave Betty Hemings as a concubine after being widowed the third time; he had six children with her, of whom the youngest was Sally Hemings.