Joseph Little Bristow (July 22, 1861 – July 14, 1944) was an American Republican politician from Kansas.Born outside Hazel Green, Kentucky, he moved to Kansas when he was twelve. He graduated from Baker University when he was 25. He edited several newspapers in Salina, Kansas before serving as a private secretary to Governor Edmund Morrill. He was President William McKinley's fourth assistant postmaster general. Bristow was elected to the U.S. Senate in 1908 and served from 1909 to 1915.