Dom Joseph Nasi (or Nassi; also known as João Miques/Micas and Dom João Migas Mendes in a Portuguese variant, Giuseppe Nasi in Italian, and as Yasef Nassi in Ottoman Turkish; 1524, Portugal – 1579, Constantinople) was a Jewish diplomat and administrator, member of the House of Mendes/Benveniste, and a nephew of Dona Gracia Mendes Nasi, and influential figure in the Ottoman Empire during the rules of both Sultan Suleiman I and his son Selim II.