Josephine County is a county located in the U.S. state of Oregon. As of the 2010 census, the population was 82,713. The county seat is Grants Pass. The county is probably named after a stream in the area called Josephine Creek, which in turn is probably named after Virginia Josephine Rollins Ort.Josephine County comprises the Grants Pass, OR Metropolitan Statistical Area, which is included in the Medford-Grants Pass, OR Combined Statistical Area.