Lake St. Joseph is a large lake in Kenora District and Thunder Bay District in Northwestern Ontario, Canada. It is in the James Bay drainage basin and is the source of the Albany River. The east end of the lake can be reached using Ontario Highway 599 from the town of Ignace, 260 kilometres (160 mi) to the south on Ontario Highway 17. The nearest town is Pickle Lake, 30 kilometres (19 mi) north along Highway 599.