Lawrence County is a county located in the U.S. state of Kentucky. As of the 2010 census, the population was 15,860. Its county seat is Louisa. The county is named for James Lawrence, and co-founded by Isaac Bolt, who served as a Lawrence County Commissioner and Justice of the Peace.Lawrence County is the home of bluegrass music and country music star Ricky Skaggs. It is the birthplace of the late Chief Justice of the United States Frederick Moore Vinson and former Kentucky Governor Paul E.