The Lenawee County Courthouse is a county courthouse located at 309 North Main Street (M-52) in the city of Adrian in central Lenawee County, Michigan. It was designated as a Michigan Historic Site on November 14, 1974 and later added to the National Register of Historic Places on February 28, 1991.The Lenawee County Courthouse is located at the corner of M-52 (known locally at this point as North Main Street) and West Front Street.