Mantralayam is a village in Kurnool district in Andhra Pradesh, India. It lies on the banks of the Tungabhadra river on the border with neighbouring Karnataka state. It is also called as Manchale. This town is noted for the holy presence of the Vrindavana (sacred burial) of Guru Raghavendra Swami, a Madhwa saint and follower of Sri Madhwacharya.