Matelica is a comune (municipality) of the Province of Macerata in the Italian region of Marche. Located about 60 kilometres (37 mi) southwest of Ancona and 35 kilometres (22 mi) west of Macerata, it extends over an area of 81.04 square kilometres (31.29 sq mi) and has a population of 10,129 inhabitants (as of 31 December 2013).