The Meathouse Fork is a tributary of Middle Island Creek, 19.7 miles (31.7 km) long, in north-central West Virginia in the United States. Via Middle Island Creek and the Ohio River, it is part of the watershed of the Mississippi River, draining an area of 64.6 square miles (167 km2) in a rural region on the unglaciated portion of the Allegheny Plateau.The Meathouse Fork's entire course and watershed are in southern and central Doddridge County.