Mezezius (/mɨˈziːʒəs/; Greek: Μιζίζιος; Armenian: Մժէժ, Mžēž or Mzhezh) was an Armenian noble who served as a general of Byzantium, later usurping the Byzantine throne in Sicily from 668 to 669.According to a letter from Pope Gregory II to Emperor Leo III, he was Count of the Opsikion, the Imperial retinue (Latin: obsequium), and a later Syriac chronicle describes him as a patrikios.