Middlesex Centre is a township in south-western Ontario, Canada. It is located to the north and west of London and is in Middlesex County. The Corporation of the Township of Middlesex Centre formed on January 1, 1998, with the amalgamation of the former Townships of Delaware, Lobo, and London (not to be confused with the adjacent City of London). It is part of the London census metropolitan area.Middlesex Centre is located halfway between two of the five Great Lakes.