Mimulus bicolor is a species of monkeyflower known by the common name yellow and white monkeyflower. It is endemic to California, where it grows in the mountains and foothills from the Klamath Range through the Sierra to the Tehachapi Mountains. It grows in moist or wet areas, often on clay soils. This is an annual herb producing a hairy, erect stem 4 to 27 centimeters tall. The linear to nearly oval leaves are each up to 3 centimeters long and arranged in opposite pairs about the stem.