Minnesota State Highway 220 (MN 220) is a regional trunk highway in northwest Minnesota, which runs from its intersection with U.S. Highway 75 in Climax and continues north to its northern terminus at its intersection with State Highway 11 near Drayton, North Dakota. The route runs along and near the Red River.For part of its route (4 miles), Highway 220 runs together with U.S. Highway 2 in the city of East Grand Forks.Highway 220 is 79 miles (127 km) in length.