Molecular Systems Biology is an open-access peer-reviewed scientific journal publishing research within systems biology at the molecular level, including genomics, proteomics, metabolomics, microbial systems, the integration of cell signaling and regulatory networks, and synthetic biology.The journal was published by Nature Publishing Group together with the European Molecular Biology Organization since its launch in March 2005, until December 2013, when EMBO press was started.According to the Journal Citation Reports, the journal had a 2014 impact factor of 10.872, ranking it 10th out of 289 journals in the category "Biochemistry & Molecular Biology".