Nathaniel Macon (December 17, 1757 – June 29, 1837) was an American politician who served as a U.S. Senator and Representative from North Carolina. During his political career he was spokesman for the Old Republican faction of the Democratic-Republican Party that wanted to strictly limit the United States federal government. Macon was born near Warrenton, North Carolina, and attended the College of New Jersey and served briefly in the American Revolutionary War.