State Route 397 (SR 397) is a state highway in the U.S. state of Nevada. It runs from State Route 860 near Derby Field east on Westergard Road and north on Meridian Road into Lovelock. After passing under Interstate 80/U.S. Route 95, it turns northeast on Amherst Avenue and ends at State Route 398, two blocks southeast of State Route 396 (old U.S. Route 40).