The Niccoline Chapel (Italian: Cappella Niccolina) is a chapel in the Apostolic Palace in Vatican City. It is especially notable for its fresco paintings by Fra Angelico (1447–1451) and his assistants, who may have executed much of the actual work. The name is derived from its patron, Pope Nicholas V, who had it built for use as his private chapel.The chapel is located in the Tower of Innocent III, in the most ancient part of the Apostolic Palace.