State Route 25 (SR 25) is an Ohio State Route that runs between Cygnet and Toledo in the US state of Ohio. The 34.77 miles (55.96 km) of SR 25 that lie within the state serve as a major highway. Some of the highway is listed on the National Highway System. Various sections are rural four-lane-lane highways and urbanized four-lane divided highways. SR 25 passes through farmland, commercial and residential properties.Between Cygnet and Perrysburg it is the relic of an old U.S.