State Route 349 (SR 349) is a north–south state highway in south-central Ohio. State Route 349 has its southern terminus is at State Route 93 in Wellston. Its northern terminus is at State Route 160 in Hamden. Besides providing a shortcut between State Route 93 and State Route 160 around Hamden, State Route 349 allows access to Lake Alma State Park in Vinton County.