State Route 558 (SR 558) is a 15.74-mile (25.33 km) state route that runs between Salem and East Palestine in the US state of Ohio. Most of the route is a rural two-lane highway and passes through farmland, woodland and residential properties.The highway was first signed in 1937 on much the same alignment as today. SR 558 replaced the SR 154 designation of the highway which dated back to 1923; SR 194 ran between Lisbon and East Palestine.