State Route 63 (SR 63) is a 11.74-mile (18.89 km) long east–west state highway located in the southwestern portion of the U.S. state of Ohio. The western terminus of SR 63 is at a trumpet interchange with SR 4 on the western outskirts of Monroe. Its eastern terminus is at a signalized intersection with US 42, SR 48 and SR 123 in downtown Lebanon.The westernmost portion of SR 63 between SR 4 and I-75 is a four-lane divided highway. It is signed as Hamilton–Lebanon Road.