Ohio wine (or "Ohioan wine") refers to wine made from grapes grown in the U.S. state of Ohio. Historically, this has been wine grown from native American species of grapes (such as Vitis labrusca), not European wine grapes, although hybrid and Vitis vinifera grapes are now common in Ohio. Currently, over 110 commercial wineries operate in Ohio, and there are five designated American Viticultural Areas partially or completely located within the state.