Pedro Opaso Letelier (July 20, 1876 - April 9, 1957) was a Chilean politician and provisional vice president of Chile in 1931.He was born in Talca, the son of Ursicino Opaso and Margarita Letelier. He completed his studies in his native city, and then attended the Universidad de Chile, where he became a physician. He started his political career as the first mayor of the city of Río Claro. In 1920 Opaso was named minister in several occasions as a representative of the Democratic Liberal Party.