Potamonautidae is a family of freshwater crabs endemic to tropical parts of Africa and adjacent islands, including Madagascar, the Seychelles, Zanzibar, Mafia, Pemba, Bioko, São Tomé, Príncipe and Sherbro Island. It comprises 18 extant genera and 138 extant species. Fossil remains dating from the Late Miocene period have been attributed to the family Potamonautidae.It comprises the following subfamilies and genera: