Preston is a ghost town in Wharton County in the U.S. state of Texas. The one-time settlement was located in the land grant belonging to Old Three Hundred settler John Huff near an important north-south trail. During the early years of the Republic of Texas lots were sold and a town took shape. Postal service began in 1839 and ceased in 1857. The only evidence that a town existed is an old cemetery near Farm to Market Road 1096 (FM 1096) south of Iago.