Proactiv is a brand of acne treatment and skin-care products distributed by direct marketing company Guthy-Renker. Developed by Drs. Katie Rodan and Kathy Fields in 1995, Proactiv consists of a cleanser and lotion that contain 2.5 percent benzoyl peroxide, a lower concentration than in prescription-strength acne treatments, and a toner that contains glycolic acid. The three-step kit is also available as Gentle Formula, which contains salicylic acid instead of benzoyl peroxide.