Route 109 is a Quebec provincial highway that runs through the western regions of Abitibi-Témiscamingue and Nord-du-Québec. It begins at Route 117 in Rivière-Héva, proceeding north approximately 59 km (36.7 mi) to Amos. From there, the highway extends 182 km (113.1 mi) to Matagami, where the road continues northwards as James Bay Road (French: Route de la Baie James). While now classified as a municipal road, the James Bay Road was part of provincial Route 109 until 2002.