The Relief of Genoa took place between 28 March 1625 and 24 April 1625, during the Thirty Years' War. It was a major naval expedition launched by Spain against the French-occupied Republic of Genoa, of which the capital Genoa was being besieged by a joint Franco-Savoyard army composed of 30,000 men and 3,000 cavalry.In 1625, when the Republic of Genoa, traditionally an ally of Spain, was occupied by French troops of the Duke of Savoy, the city underwent a hard siege.