Celia-Sandra Botha (born 25 February 1945) is a South African politician, who serves as South Africa's Ambassador to the Czech Republic. She is the former Leader of the Opposition in the National Assembly, on behalf of the Democratic Alliance and its leader, Helen Zille. She announced her intention to step down from the position after the South African general election, 2009, to become an ambassador. Her term in Prague ended in June 2013.