Highway 49 is a highway in the east central portion of the Canadian province of Saskatchewan. In the west on Highway 35 are the neighboring communities of Fosston and Hendon. From Highway 35, Highway 49 travels east to the Manitoba border, where it transitions to PTH 49. This is a primary Saskatchewan highway maintained by the provincial government and is paved for its length. Located along this highway are Kelvington, Lintlaw, Preeceville, Sturgis, Norquay, and Pelly.