Sesamothamnus lugardii (Transvaal sesame-bush, sesambos) is a species of plant in family Pedaliaceae, endemic to southern Namibia, eastern Botswana, southern Zimbabwe, and Kruger National Park in the Transvaal. It is a soft-stemmed shrub that grows alone or in scattered, small groups in hot, dry areas. The plant can grow to 4 meters in height with a very thick lower trunk, up to 1 meter in diameter, from which arise several thick branches. Flowers are white.