Sicyos macrophyllus is a rare species of flowering plant in the Cucurbitaceae, the squash family. It is endemic to Hawaii where it is present only on the island of Hawaii. It has likely been extirpated from the island of Maui. Common names include alpine bur cucumber, largeleaf bur-cucumber, and 'anunu.This is a perennial herb producing vines up to 15 meters long and 4 centimeters thick. They are supported with tendrils. The stems are slightly hairy and have black spots. The leaves are lobed.