Sossianus Hierocles (fl. 303) was a late Roman aristocrat and office-holder. He served as a praeses in Syria under Diocletian at some time in the 290s. He was then made vicarius of some district, perhaps Oriens (the East, including Syria, Palestine, and, at the time, Egypt) until 303, when he was transferred to Bithynia. It is for his anti-Christian activities in Bithynia that he is principally remembered.