Streptococcus mutans is facultatively anaerobic, Gram-positive coccus-shaped bacterium commonly found in the human oral cavity and is a significant contributor to tooth decay.It is part of the "streptococci" (plural, non-italic lowercase), an informal general name for all species in the genus Streptococcus (capitalized, italic due to its being the formal name).The microbe was first described by J Kilian Clarke in 1924.This bacterium, along with the closely related species Streptococcus sobrinus, can cohabit the mouth: Both contribute to oral disease, and the expense of differentiating them in laboratory testing is often not clinically necessary.