Thomas Hickman Williams (January 20, 1801 – May 3, 1851) was a United States Senator from Mississippi. Born in Williamson County, Tennessee, he attended the common schools, moved to Mississippi and settled in Pontotoc County, and engaged in planting. He was appointed and subsequently elected as a Democrat to the U.S. Senate to fill the vacancy caused by the resignation of James F. Trotter and served from November 12, 1838, to March 3, 1839.