Three Way is a city in Madison County, Tennessee. The population was 1,709 at the 2010 census. It is included in the Jackson, Tennessee Metropolitan Statistical Area. Before the city was officially incorporated in 1998, the area was commonly known as "Three Way" for a number of years because of the split by U.S. Route 45 along its north-south route into US 45W towards Humboldt and US 45E towards Milan.