Throw Momma from the Train is a 1987 American black comedy film directed by and starring Danny DeVito in his directorial debut. The film co-stars Billy Crystal, Rob Reiner, Anne Ramsey, Branford Marsalis, Kim Greist, and Kate Mulgrew appearing in supporting roles.The title comes from Patti Page's 1956 hit song, "Mama from the Train (A Kiss, A Kiss)". The film was inspired by the 1951 Alfred Hitchcock thriller Strangers on a Train, which also plays a role in the film.