Toxin or the Toxin symbiote is a fictional character in the Marvel Comics universe. He is the third major symbiote of the Spider-Man series, the ninth known to have appeared in the comics outside of the Planet of the Symbiotes storyline, and the first symbiote that Spider-Man considers an ally, despite temporary alliances with Venom on numerous occasions. The first host of the Toxin symbiote is former NYPD police officer Patrick Mulligan.